Essential tremor is not associated with α‐synuclein gene haplotypes
- 12 June 2003
- journal article
- Published by Wiley in Movement Disorders
- Vol. 18 (7) , 823-826
- https://doi.org/10.1002/mds.10421
Abstract
A specific allele of the NACP‐Rep1 polymorphism within the α‐synuclein promoter was found to be associated both with Parkinson's disease and essential tremor. We repeated the association study on a large series of Italian patients with essential tremor using a panel of polymorphisms within the α‐synuclein gene. Our results did not confirm the association reported previously and failed to identify a α‐synuclein specific haplotype as susceptibility factor for essential tremor. © 2003 Movement Disorder SocietyKeywords
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