The ingestion of fruits is known to cause urticaria, diarrhea, angioneurotic edema, palatal itching, migraine, allergic rhinitis, asthma, and rarely, purpura. A search through the literature failed to reveal any previously observed case of anaphylactoid shock due to ingestion of an orange. Our experience with such a case prompted this report. Report of a Case A 48-year-old woman was seen in the emergency room of Hahnemann Medical College and Hospital at 4:30 p. m. on March 25, 1959, complaining of dizziness and a diffuse skin rash. She had eaten a fresh orange at noon on that day. By 3 p. m. she had developed itching at the neck and malaise. She left her job at a textile mill and shortly thereafter felt dizzy, thirsty, and chilly and was brought to the emergency room in shock. She stated that all other foods eaten on that day had been eaten frequently recently,