Thyroxine Depression of Mouse Thyroid Iodide Trap Activity
- 1 December 1954
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 87 (3) , 578-580
- https://doi.org/10.3181/00379727-87-21449
Abstract
Chronic treatment of C3H mice with thyroxine for 5-14 days was no more effective than hypophysectomy in depressing the thyroid iodide trap. Thyroid stimulating hormone (TSH) had some stimulating effect on the activity of the thyroid iodide trap. The activity of the mouse thyroid iodide trap is much greater than that of the rat and either thyroxine or hypophysectomy are ineffective in completely depressing the iodide trap. The combination of TSH and propylthiouracil caused a greater response, but insufficient to serve as an assay technique for thyrotrophin.Keywords
This publication has 0 references indexed in Scilit: