Irradiation crosslinking of the polytetrapeptide of elastin and compounding to dacron to produce a potential prosthetic material with elasticity and strength

Publisher Website
Google Scholar
Abstract
The poly(tetra peptide), H- (L·Val1-L·Pro2-Gly3-Gly4)n-L·Val-OMe, which is a recurring sequence in tropoelastin the precursor protein of the elastic fiber, has been irradiation crosslinked to produce an elastomeric material with limited strength. When a material such as a Dacron fabric is impregnated by the coacervate phase of the poly(tetra peptide) prior to irradiation crosslinking at 50 Mrad, the crosslinked product exhibits stress–strain curves with good elastomeric properties and high strength. In addition to the stress-strain curves, the material is characterized by scanning electron microscopy.