The Membrane-bound Hydrogenase Reduces Cytochromec552inHydrogenobacter thermophilusstrain TK-6

Abstract
The cells of Hydrogenobacter thermophilus strain TK-6 contain only a membrane-bound hydrogenase. The membrane-bound hydrogenase was partially purified from the cells of H. thermophilus after solubilization by alkaline treatment. The hydrogenase activity was increased up to 10-fold by the addition of anionic detergents. The hydrogenase reacted with cytochrome c552 obtained from the same strain in the presence of an anionic detergent. Our experiments show cytochrome c552 is a natural electron acceptor for the membrane-bound hydrogenase, and an electron transport system in H. thermophilus strain TK-6 is proposed.

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