Characterization of ascyllo-inositol-containing sialyloligo-saccharide from normal human urine

Publisher Website
Google Scholar
Abstract
Three inositol‐containing sialyloligosaccharides were isolated from normal human urine. Structural studies including gas—liquid chromatography of mono‐ and disaccharide derivatives, methylation analysis, mass spectrometry and glycosidase treatments indicated the structure NeuAc (α2–3)Gal(β1‐0)scyllo‐inositol for one of the oligosaccharides isolated. This provides the first evidence for the natural occurrence of a scyllo‐inositol glycoside in biological material. The two other oligosaccharides isolated were identified as two isomers of NeuAc(α2–3)Gal(β1‐0)myo‐inositol, which have not been identified in normal urine before.