Versican splice variant messenger RNA expression in normal human Achilles tendon and tendinopathies

Open Access

1 June 2004

journal article
Published by Oxford University Press (OUP) in Rheumatology

Vol. 43 (8) , 969-972
https://doi.org/10.1093/rheumatology/keh222

Abstract

Objectives. Versican is the principal large proteoglycan expressed in mid-tendon, but its role in tendon pathology is unknown. Our objective was to define the expression of versican isoform splice variant messenger ribonucleic acid (mRNA) in normal Achilles tendons, in chronic painful tendinopathy and in ruptured tendons.

Keywords

PROTEOGLYCAN.
TENDINOPATHY
VERSICAN
TENDON
VARIANT
NORMAL
SPLICE VARIANT
RNA ISOLATION
MESSENGER RNA
GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE
RHEUMATOLOGY

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