Kinetics of in vitro O-deethylation of phenacetin and 7-ethoxycoumarin by rat intestinal mucosal cells and microsomes
- 1 May 1983
- journal article
- research article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 32 (10) , 1573-1580
- https://doi.org/10.1016/0006-2952(83)90330-1
Abstract
No abstract availableKeywords
This publication has 33 references indexed in Scilit:
- Time and dose dependence of 3-methylcholanthrene-induced metabolism in rat intestinal mucosal cells and microsomesBiochemical Pharmacology, 1982
- Prediction of intestinal first-pass effect of phenacetin in the rat from enzyme kinetic data — correlation with in in vivo data using mucosal blood flowBiochemical Pharmacology, 1982
- Biphasic O-deethylation of phenacetin and 7-ethoxycoumarin by human and rat liver microsomal fractionsBiochemical Pharmacology, 1981
- Inhibition of oxidative drug metabolism in microsomesPharmacology & Therapeutics, 1980
- Separation of acetanilide and its hydroxylated metabolites and quantitative determination of “acetanilide 4-hydroxylase activity” by high-pressure liquid chromatographyAnalytical Biochemistry, 1979
- An improved method for preparing rat small intestine microsomal fractions for studying drug metabolismAnalytical Biochemistry, 1979
- Dependence of Km and Vmax on substrate concentration for rat hepatic microsomal ethylmorphine N-demethylaseBiochemical Pharmacology, 1973
- Aminopyrine demethylase kinetic evidence for multiple microsomal activitiesBiochemical Pharmacology, 1970
- Effects of Steroid Hormones on Drug-metabolizing Enzyme Systems in Liver Microsomes*The Journal of Biochemistry, 1968
- Biochemistry of dystrophic muscle. Mitochondrial succinate-tetrazolium reductase and adenosine triphosphataseBiochemical Journal, 1961