The Growth of Pasteurella tularensis in the Yolk Sac of Developing Chick Embryo

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Abstract
Growth of P. tularensis in the chick embryo following inoculation of infective material into the yolk-sac of 7-day-old embryos was demonstrated. Serial transmission through embryos for 6 and 13 passages did not decrease the virulence of the organisms for white mice. The chicken embryo appears to be as susceptible as white mice to infection with P. tularensis and the cone, of organisms in the tissues and fluids of the chick embryo is as great as that obtained in the tissues of white mice infected with this agent. The infection in chick embryos is generalized as judged by the distribution of organisms in various tissues and fluids.

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