Reactions of Dextrans with Antiserums of Rabbits Immunized with S. typhi

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Abstract
Solns. of dextran, both in the unhydrolyzed or native form and in the partially hydrolyzed or clinical form, gave precipitation reactions with antisera of rabbits immunized with Salmonella typhosa, including vaccines prepared for human typhoid prophylaxis. Reactions also occurred with antisera of some other Salmonella, particularly S. oranienburg. Among 5 samples of clinical dextran that had previously been used in studies by others in an Army hospital, 4 that had given fairly frequent untoward reactions had greater capacities to fix complement with S. typhi antisera than did the one that had given no untoward reactions.