Discrimination between Cases of Duodenal Ulcer and Gastritis on the Basis of Putative Virulence Factors of Helicobacter pylori
Open Access
- 1 June 2002
- journal article
- research article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 40 (6) , 2244-2246
- https://doi.org/10.1128/jcm.40.6.2244-2246.2002
Abstract
The BabA, cagA , and vacA statuses of 827 Helicobacter pylori isolates were used in logistic regression models to discriminate duodenal ulcer from gastritis. Only BabA was a candidate for a universal virulence factor, but the low c statistic value (0.581) indicates that none of these factors were helpful in predicting the clinical presentation.Keywords
This publication has 8 references indexed in Scilit:
- Distinctiveness of Genotypes ofHelicobacter pyloriin Calcutta, IndiaJournal of Bacteriology, 2000
- Disease‐specific Helicobacter pylori Virulence Factors: The Unfulfilled PromiseHelicobacter, 2000
- Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesinProceedings of the National Academy of Sciences, 1999
- Relationship of vacA Genotypes of Helicobacter pylori to cagA Status, Cytotoxin Production, and Clinical OutcomeHelicobacter, 1998
- Helicobacter pylori Adhesin Binding Fucosylated Histo-Blood Group Antigens Revealed by RetaggingScience, 1998
- The complete genome sequence of the gastric pathogen Helicobacter pyloriNature, 1997
- Mosaicism in Vacuolating Cytotoxin Alleles of Helicobacter pyloriJournal of Biological Chemistry, 1995
- A plasmid system for high-level expression and in vitro processing of recombinant proteinsGene, 1993