A tris(macrocycle) that exhibits H-bond-induced blockage of the cation channel faction in a phospholipid bilayer
- 1 January 1996
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 18,p. 2147-2148
- https://doi.org/10.1039/cc9960002147
Abstract
An indole-terminated tris(macrocyclic) compound, designed to be a channel-former, is an effective carrier in bluk membranes but fails to function in a lipid bilayer owing to hydrogen bond formation which blocks the channel.Keywords
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