Age-Related Alterations in Membrane Lipid and Protein Interactions: Arrhenius Studies of Microsomal Glucose-6-Phosphatase
- 1 January 1977
- journal article
- research article
- Published by S. Karger AG in Gerontology
- Vol. 23 (5) , 342-349
- https://doi.org/10.1159/000212206
Abstract
Arrhenius plots of glucose-6-phosphatase (EC 3.1.3.9) activity in liver microsomes from 6 mo. old rats (young) showed discontinuities at 39, 30, 20 and 12.degree. C and change in activation energy at 20.degree. C. The enzyme activity in kidney microsomes of young rats showed essentially the same thermal discontinuities. In liver microsomes of 24 mo. old rats (old) the enzyme showed discontinuities at 38, 30, 24 and 16.degree. C but not at 12.degree. C and the activation energy changed at 24.degree. C. In kidney microsomes of old rats discontinuities were seen at 38, 31, 22, 16 and 12.degree. C and the activation energy was constant from 0 to 41.degree. C. The interactions of membrane components may be altered with age.This publication has 1 reference indexed in Scilit:
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951