Interstrain differences in bitter taste responses in mice
- 1 January 1985
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemical Senses
- Vol. 10 (1) , 51-55
- https://doi.org/10.1093/chemse/10.1.51
Abstract
Interstrain differences in bitter taste responses were examined using inbred strains of mice. Taste responses were recorded from the glossopharyngeal and chorda tympani nerves of SWR/J, LP/J, BDP/J and DBA/2J mice. There were large differences in the magnitude of responses to sucrose octaacetate (SOA) in both the glossopharyngeal and chorda tympani nerves of SWR/J mice as compared with the other strains of mice. SOA thresholds of SWR/J mice were 10 −7 – −6 M, whereas they were – 10 −4 M in LP/J mice. On the other hand, no appreciable differences were observed in the responses to quinine hydrochloride and pnenyl-thio-carbamide. The results obtained in the present experiments fully explain the findings in behavioral studies showing that only SWR/J mice avoid SOA solutions whereas other strains do not.This publication has 0 references indexed in Scilit: