Effects of Postmenopausal Estrogen Replacement on the Concentrations and Metabolism of Plasma Lipoproteins
Open Access
- 24 October 1991
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 325 (17) , 1196-1204
- https://doi.org/10.1056/nejm199110243251702
Abstract
Postmenopausal estrogen-replacement therapy may reduce the risk of cardiovascular disease, and this beneficial effect may be mediated in part by favorable changes in plasma lipid levels. However, the effects on plasma lipoprotein levels of postmenopausal estrogens in the low doses currently used have not been precisely quantified, and the mechanism of these effects is unknown.Keywords
This publication has 41 references indexed in Scilit:
- Effects of estrogen on low density lipoprotein metabolism in males. Short-term and long-term studies during hormonal treatment of prostatic carcinoma.Journal of Clinical Investigation, 1989
- Lipid alterations and decline in the incidence of coronary heart disease in the Helsinki Heart StudyJAMA, 1988
- Cholesterol efflux from cultured adipose cells is mediated by LpAI particles but not by LpAI:AII particlesBiochemical and Biophysical Research Communications, 1987
- Biologic Effects of Transdermal EstradiolNew England Journal of Medicine, 1986
- Very low density lipoprotein triglyceride kinetics during hepatic lipase suppression by estrogenFEBS Letters, 1985
- Metabolism of apolipoprotein B in large triglyceride-rich very low density lipoproteins of normal and hypertriglyceridemic subjects.Journal of Clinical Investigation, 1984
- The Lipid Research Clinics Coronary Primary Prevention Trial results. II. The relationship of reduction in incidence of coronary heart disease to cholesterol loweringJAMA, 1984
- MENOPAUSAL OESTROGEN THERAPY AND PROTECTION FROM DEATH FROM ISCHAEMIC HEART DISEASEThe Lancet, 1981
- Decreased Risk of Fractures of the Hip and Lower Forearm with Postmenopausal Use of EstrogenNew England Journal of Medicine, 1980
- Mechanism of Hypertriglyceridaemia Associated with Contraceptive SteroidsHormone and Metabolic Research, 1973