Studies on the Mechanism of Phosphorus Excretion in Vitamin D Resistant Rickets
- 1 January 1966
- journal article
- research article
- Published by S. Karger AG in Nephron
- Vol. 3 (1) , 40-58
- https://doi.org/10.1159/000179424
Abstract
Two patients with vitamin D resistant rickets respond to a high P intake by a positive Ca balance. The response to a Ca infusion suggests a parathyroid effect on phosphaturia but the size and histology of the parathyroid glands in one patient was normal. A circadian P excretion rhythum was present. Studies of the effect of glucose on the renal handling of P in these patients suggest an inhibitory effect which is lacking in normals. It is postulated that 1 of 2 metabolic pathways for the renal tubular reabsorption of P is absent in vitamin D resistant rickets.This publication has 1 reference indexed in Scilit:
- A Rapid Calcium Infusion Test for HyperparathyroidismJournal of Clinical Endocrinology & Metabolism, 1962