Congenital Malformations
Open Access
- 22 July 1976
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 295 (4) , 204-207
- https://doi.org/10.1056/nejm197607222950406
Abstract
Congenital malformations are a common cause of illness, handicapping conditions and death. The incidence varies with the age of the person being evaluated. It is highest among spontaneous abortions, with many of the abnormalities incompatible with survival. About 2 per cent of newborns have a major malformation. Additional malformations not detected at birth, such as renal anomalies and cardiac defects, become apparent in succeeding years.TerminologySeveral terms have been adapted for use in describing the nature of malformation. Anomaly and malformation are considered synonymous for a structural abnormality. A major malformation has either surgical or cosmetic consequences; a minor . . .Keywords
This publication has 8 references indexed in Scilit:
- Classification, nomenclature, and naming of morphologic defectsThe Journal of Pediatrics, 1975
- Inborn Errors of MorphogenesisNew England Journal of Medicine, 1974
- Identification of chromosomal abnormalities by quinacrine-staining technique in patients with normal karyotypes by conventional analysisThe Journal of Pediatrics, 1974
- ALLELISM, NON-ALLELISM, AND GENETIC COMPOUNDS AMONG THE MUCOPOLYSACCHARIDOSESThe Lancet, 1972
- Atypical malformation syndromesThe Journal of Pediatrics, 1972
- GENETICS OF COMMON DISORDERSBritish Medical Bulletin, 1969
- The inheritance of liability to certain diseases, estimated from the incidence among relativesAnnals of Human Genetics, 1965
- Congenital Cleft Lip and PalateAmerican Journal of Diseases of Children, 1961