DIFFERENTIAL CHARACTERISTICS INVITRO AND INVIVO OF SEVERAL SUBSTRAINS OF BCG .4. IMMUNIZING EFFECTIVENESS
- 1 January 1956
- journal article
- research article
- Published by Elsevier
- Vol. 74 (5) , 699-717
- https://doi.org/10.1164/artpd.1956.74.5.699
Abstract
With the injection of large doses of BCG vaccine an animal may produce antibodies even though vaccinating bacilli do not have a chance to multiply in vivo. With smaller doses of vaccine, isoniazid chemoprophylaxis interferes with the development of immunity by inhibiting bacterial multiplication and hence preventing the accumulation of antigenic material.Keywords
This publication has 1 reference indexed in Scilit:
- ANTITUBERCULOUS IMMUNITY INDUCED IN RED MICE (CLETHRIONOMYS G. GLAREOLUS SCHREB.) BY VACCINATION WITH LIVING BCGActa Pathologica Microbiologica Scandinavica, 2009