Characterization of a Group of Transposed Human VKGenes
- 1 January 1986
- journal article
- research article
- Published by Walter de Gruyter GmbH in Biological Chemistry Hoppe-Seyler
- Vol. 367 (2) , 751-756
- https://doi.org/10.1515/bchm3.1986.367.2.751
Abstract
A genomic region with three VK pseudogenes which has been transposed to chromosome 22 is characterized by detailed restriction mapping. A number of subclones are described one of which proved useful to establish an allelic restriction fragment length polymorphism (RFLP) in the region. Allelic and duplication-derived restriction site differences in cosmid clones are discussed with respect to possible problems in genomic walking experiments.This publication has 7 references indexed in Scilit:
- Detection of specific sequences among DNA fragments separated by gel electrophoresisPublished by Elsevier ,2006
- ORIGIN OF IMMUNE DIVERSITY: GENETIC VARIATION AND SELECTIONAnnual Review of Biochemistry, 1985
- A large section of the gene locus encoding human immunoglobulin variable regions of the Kappa type is duplicatedJournal of Molecular Biology, 1985
- Organization and evolution of a gene cluster for human immunoglobulin variable regions of the kappa typeJournal of Molecular Biology, 1984
- REVIEWHoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1984
- Localization of human immunoglobulin kappa light chain variable region genes to the short arm of chromosome 2 by in situ hybridization.Proceedings of the National Academy of Sciences, 1982
- Chromosomal location of human kappa and lambda immunoglobulin light chain constant region genesThe Journal of Experimental Medicine, 1982