Novel Cathepsin D Inhibitors Block the Formation of Hyperphosphorylated Tau Fragments in Hippocampus
Open Access
- 1 April 2000
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 74 (4) , 1469-1477
- https://doi.org/10.1046/j.1471-4159.2000.0741469.x
Abstract
Lysosomal disturbances may be a contributing factor to Alzheimer's disease. We used novel compounds to test if suppression of the lysosomal protease cathepsin D blocks production of known ...Keywords
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