Collisional spectroscopy in structural characterization of melanins 2—laser desorption experiments on bio- and synthetic tryptophan melanins
- 15 March 1988
- journal article
- research article
- Published by Wiley in Journal of Mass Spectrometry
- Vol. 15 (6) , 353-355
- https://doi.org/10.1002/bms.1200150608
Abstract
Melanins1 are naturally occurring macromolecules whose structural complexity appeared evident from the first researches of Quilico.2 Their structural characterization remains a difficult problem, mainly due to the physico‐chemical properties of such compounds. Melanins are insoluble in organic solvents as well as aqueous solutions and are infusible. Consequently the traditional chemical degradation and physicochemical methods such as ultraviolet, infrared, 1H and 13C nuclear magnetic resonance, ESR (electron spin resonance), XPS (X‐rays photoelectron spectroscopy) and X‐ray diffraction have led, until now, to limited information on melanin chemical structure1,3.This publication has 4 references indexed in Scilit:
- A simple instrumental approach for lasser induced ‘hard’ evaporation of samplesJournal of Mass Spectrometry, 1986
- Collision SpectroscopyPublished by Springer Nature ,1978
- Melanogenesis from tryptophan. Biogenetic experiments with harding-passey mouse melanomaCellular and Molecular Life Sciences, 1974
- Radiometric assay of tyrosinase and theoretical considerations of melanin formationAnalytical Biochemistry, 1965