Role of protein O-linked N-acetyl-glucosamine in mediating cell function and survival in the cardiovascular system
Open Access
- 15 January 2007
- journal article
- review article
- Published by Oxford University Press (OUP) in Cardiovascular Research
- Vol. 73 (2) , 288-297
- https://doi.org/10.1016/j.cardiores.2006.07.018
Abstract
There is growing recognition that the O-linked attachment of N-acetyl-glucosamine (O-GlcNAc) on serine and threonine residues of nuclear and cytoplasKeywords
This publication has 91 references indexed in Scilit:
- Location and characterization of the O-GlcNAcase active siteBiochimica et Biophysica Acta (BBA) - General Subjects, 2006
- Akt1 is dynamically modified with O‐GlcNAc following treatments with PUGNAc and insulin‐like growth factor‐1FEBS Letters, 2006
- The Pathogenesis of Myocardial Fibrosis in the Setting of Diabetic CardiomyopathyJournal of the American College of Cardiology, 2006
- O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytesExperimental & Molecular Medicine, 2005
- OGT functions as a catalytic chaperone under heat stress response: a unique defense role of OGT in hyperthermiaBiochemical and Biophysical Research Communications, 2004
- O-GlcNAc a sensor of cellular state: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stressPublished by Elsevier ,2004
- IncreasedO‐glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic β‐cellsThe FASEB Journal, 2004
- Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferaseBiochemical and Biophysical Research Communications, 2002
- Glucose Metabolism to Glucosamine Is Necessary for Glucose Stimulation of Transforming Growth Factor-α Gene TranscriptionJournal of Biological Chemistry, 1996
- NIDDM as unfavorable factor to the postinfarctual ventricular function in the elderlyCoronary Artery Disease, 1995