Reduction of Toxic Metabolite Formation of Acetaminophen
- 1 March 2002
- journal article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 291 (4) , 1089-1094
- https://doi.org/10.1006/bbrc.2002.6541
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- Role of CYP1A2 in the Hepatotoxicity of Acetaminophen: Investigations UsingCyp1a2Null MiceToxicology and Applied Pharmacology, 1998
- Ethylene glycol poisoning treated by intravenous 4-methylpyrazoleIntensive Care Medicine, 1998
- Oxidation of Acetaminophen to Its Toxic Quinone Imine and Nontoxic Catechol Metabolites by Baculovirus-Expressed and Purified Human Cytochromes P450 2E1 and 2A6Chemical Research in Toxicology, 1998
- Inhibition of human hepatic cytochrome P4502E1 by azole antifungals, CNS-active drugs and nonsteroidal anti-inflammatory agentsXenobiotica, 1998
- Cimetidine as adjunctive treatment for acetaminophen overdoseHuman & Experimental Toxicology, 1995
- Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kineticsChemical Research in Toxicology, 1993
- Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by Human CYP3A4Biochemical Pharmacology, 1993
- Molecular Aspects of Paracetamol-Induced Hepatotoxicity and its Mechanism-Based PreventionDrug Metabolism Reviews, 1992
- Acetaminophen activation by human liver cytochromes P450IIE1 and P450IA2Archives of Biochemistry and Biophysics, 1989
- Immunochemical and catalytical studies on hepatic coumarin 7-hydroxylase in man, rat, and mouseBiochemical Pharmacology, 1988