ERYTHEMA ELEVATUM DIUTINUM - CUTANEOUS VASCULITIS, IMPAIRED CLOT LYSIS, AND RESPONSE TO PHENFORMIN

  • 1 January 1977
    • journal article
    • research article
    • Vol. 4  (1) , 103-112
Abstract
Erythema elevatum diutinum consists of chronic, often painful, predominantly acral skin nodules and plaques, associated with an underlying cutaneous vasculitis. A patient with this disorder is described, who had an elevated sedimentation rate [erythrocyte], positive antinuclear factor, impaired clot lysis and dramatic fibrin deposition in skin vessel walls. A variety of treatments were without benefit in this case as in most others, but phenformin [fibrinolytic agent] produced marked improvement for periods of 11 and 16 mo. on 2 occasions. Protection of the lesions from minor trauma is also important.

This publication has 0 references indexed in Scilit: