Acid-Ethanol-Extractable Nonsuppressible Insulin-Like Activity (NSILA-S) during Pregnancy and the Puerperium, and in Cord Serum at Term*

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Abstract
A longitudinal study of serum NSILA-S during normal human pregnancy and the puerperium has demonstrated that levels rose progressively during pregnancy and returned to nonpregnant values about 48 h after delivery. Low concentrations were defined within the feto-placental circulation at term. Cord arterial and venous levels were equivalent, but there was no significant correlation between these and matched maternal values (J Clin Endocrinol Metab48: 695, 1979)