Action of staphylococcal ?-toxin on membranes: Some recent advances

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Abstract
Summary Recent developments in the area of Staphylococcal α-toxin studies are presented which modify the concepts previously held with respect to both biological and physical properties of α-toxin. New data concerning the nature of the binding site for α-toxin on rabbit erythrocyte membranes and a model to explain the various observed complexes of α-toxin and membrane receptor are discussed. Finally, evidence suggesting that Staphylococcal α-toxin is a potent demyelinating agent is presented.