EFFECTS OF CENTRAL DEPRESSANTS ON THE EVOKED POTENTIALS IN THE INFERIOR COLLICULUS CAUSED BY ACOUSTIC STIMULI IN THE CAT

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Abstract
The effects of intravenous infusion of the central depressants such as pento-barbital sodium, chloralose, urethane, ethyl alcohol and chlorpromazine on the evoked potential caused by click stimulation were observed in the inferior colliculus of the encephale isole cat. The collicular acoustic evoked potential in unanesthetized animal was consisted of the spike pattern with short duration, and was relatively stable against the environmental changes. All depressants used decreased the amplitude of the collicular evoked potential in proportion to increase in the infused doses and did not affect either duration or latency of the potential. The facilitatory effects of the small doses of pentobarbital sodium and chloralose on the cortical acousti evoked potential were discussed in respect to the site of action in the supra-thalamic levels.