EXPRESSION OF OKM5 ANTIGEN ON HUMAN KERATINOCYTES INVITRO UPON STIMULATION WITH GAMMA-INTERFERON
- 1 January 1986
- journal article
- research article
- Vol. 66 (6) , 527-530
Abstract
Using murine monoclonal antibodies against human OKM5, OKM1 and HLA-DR antigens antigenic characteristics of freshly separated human epidermal cells (EC) and those of EC cultured in the presence of Interferon-.gamma. (IFN-.gamma.) were studied. After 8-12 days of culture, primarily OKM1- OKM5- HLA-DR- keratinocytes displayed OKM5 and HLA-DR antigens when exposed to IFN-.gamma.. Our data support the concept, that human keratinocytes may possess accessory cell functions.This publication has 3 references indexed in Scilit:
- Human Epidermal Cells Synthesize HLA-DR Alloantigens In Vitro upon Stimulation with γ-InterferonJournal of Investigative Dermatology, 1985
- Human interferon-? induces expression of HLA-DR on keratinocytes and melanocytesArchives of Dermatological Research, 1985
- EXPRESSION OF HLA-DR (IA LIKE) ANTIGEN ON EPIDERMAL-KERATINOCYTES IN HUMAN DERMATOSES1984