Exploration of the Dopamine Transporter: In Vitro and In Vivo Characterization of a High-Affinity and High-Specificity Iodinated Tropane Derivative (E)-N-(3-iodoprop-2-enyl)-2β-carbomethoxy- 3β-(4′-methylphenyl)nortropane (PE2I)
- 1 May 1998
- journal article
- Published by Elsevier in Nuclear Medicine and Biology
- Vol. 25 (4) , 331-337
- https://doi.org/10.1016/s0969-8051(97)00224-2
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- A new iodinated tropane derivative (?-CDIT) for in vivo dopamine transporter exploration: Comparison with ?-CITSynapse, 1997
- Synthesis and Ligand Binding of Nortropane Derivatives: N-Substituted 2β-Carbomethoxy-3β-(4‘-iodophenyl)nortropane and N-(3-Iodoprop-(2E)-enyl)-2β-carbomethoxy-3β-(3‘,4‘-disubstituted phenyl)nortropane. New High-Affinity and Selective Compounds for the Dopamine TransporterJournal of Medicinal Chemistry, 1997
- Practical benefit of [123I]FP-CIT SPET in the demonstration of the dopaminergic deficit in Parkinson's diseaseEuropean Journal of Nuclear Medicine and Molecular Imaging, 1997
- Synthesis and Characterization of Radioiodinated N-(3-Iodopropen-1-yl)-2.beta.-carbomethoxy-3.beta.-(4-chlorophenyl)tropanes: Potential Dopamine Reuptake Site Imaging AgentsJournal of Medicinal Chemistry, 1994
- Positron emission tomographic imaging of the dopamine transporter with 11C‐WIN 35,428 reveals marked declines in mild Parkinson's diseaseAnnals of Neurology, 1993
- SPECT imaging of dopamine and serotonin transporters with [123I]?-CIT. Binding kinetics in the human brainJournal Of Neural Transmission-Parkinsons Disease and Dementia Section, 1993
- High‐affinity binding of [125I]RTI‐55 to dopamine and serotonin transporters in rat brainSynapse, 1992
- [125I]RTI-55: a potent ligand for dopamine transportersEuropean Journal of Pharmacology, 1991
- GBR 12783, a potent and selective inhibitor of dopamine uptake: Biochemical studies in vivo and ex vivoEuropean Journal of Pharmacology, 1986
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976