Opportunities for enzyme engineering in natural product biosynthesis
- 5 February 2009
- journal article
- review article
- Published by Elsevier in Current Opinion in Chemical Biology
- Vol. 13 (1) , 35-42
- https://doi.org/10.1016/j.cbpa.2009.01.005
Abstract
No abstract availableKeywords
This publication has 38 references indexed in Scilit:
- Metabolic reprogramming of periwinkle plant cultureNature Chemical Biology, 2009
- Dynamic thiolation–thioesterase structure of a non-ribosomal peptide synthetaseNature, 2008
- Structural basis for the selectivity of the external thioesterase of the surfactin synthetaseNature, 2008
- Optimizing Glycosyltransferase Specificity via “Hot Spot” Saturation Mutagenesis Presents a Catalyst for Novobiocin GlycorandomizationChemistry & Biology, 2008
- Deconstruction of Iterative Multidomain Polyketide Synthase FunctionScience, 2008
- Crystal structure and functional analysis of tetracenomycin ARO/CYC: Implications for cyclization specificity of aromatic polyketidesProceedings of the National Academy of Sciences, 2008
- Strictosidine Synthase: Mechanism of a Pictet−Spengler Catalyzing EnzymeJournal of the American Chemical Society, 2007
- Rapid Identification of Enzyme Variants for Reengineered Alkaloid Biosynthesis in PeriwinkleChemistry & Biology, 2007
- Directed evolution of aryl carrier proteins in the enterobactin synthetaseProceedings of the National Academy of Sciences, 2007
- The evolving role of natural products in drug discoveryNature Reviews Drug Discovery, 2005