Monte Carlo study of the selectivity of calcium channels: improved geometrical model
- 20 July 2002
- journal article
- research article
- Published by Taylor & Francis in Molecular Physics
- Vol. 100 (14) , 2361-2368
- https://doi.org/10.1080/00268970210125304
Abstract
An extended model of a calcium channel is described involving a channel with a finite length. With this new geometry the channel is still selective but less so than in an infinite cylinder geometry (Boda, D., Busath, D. D., Henderson, D., and Sokolowski, S., 2000, J. phys. Chem. B, 104, 8903). The selectivity of the channel depends on the width and length of the channel filter but is not significantly affected by changes in the size of the entry vestibules. Interestingly, changes in the size of the entry vestibules do affect the details of the concentration profiles of some of the ions.Keywords
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