Successful in vivo blockade of CD25 (high-affinity interleukin 2 receptor) on T cells by administration of humanized anti-Tac antibody to patients with psoriasis
- 1 September 2000
- journal article
- clinical trial
- Published by Elsevier in Journal of the American Academy of Dermatology
- Vol. 43 (3) , 448-458
- https://doi.org/10.1067/mjd.2000.106515
Abstract
No abstract availableKeywords
This publication has 28 references indexed in Scilit:
- CD69, HLA-DR and the IL-2R Identify Persistently Activated T Cells in Psoriasis Vulgaris Lesional Skin: Blood and Skin Comparisons by Flow CytometryJournal of Autoimmunity, 2000
- Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesionsJournal of Clinical Investigation, 1999
- The Majority of Epidermal T Cells in Psoriasis Vulgaris Lesions can Produce Type 1 Cytokines, Interferon-γ, Interleukin-2, and Tumor Necrosis Factor-α, Defining TC1 (Cytotoxic T Lymphocyte) and TH1 Effector Populations:1 a Type 1 Differentiation Bias is also Measured in Circulating Blood T Cells in Psoriatic PatientsJournal of Investigative Dermatology, 1999
- Treatment of Recalcitrant Plaque Psoriasis with a Humanized Non-depleting Antibody to CD4Journal of Autoimmunity, 1998
- IL-10 is a key cytokine in psoriasis. Proof of principle by IL-10 therapy: a new therapeutic approach.Journal of Clinical Investigation, 1998
- Rediscovering mycophenolic acid: A review of its mechanism, side effects, and potential usesJournal of the American Academy of Dermatology, 1997
- Interferon-gamma differentially regulates interleukin-12 and interleukin-10 production in leprosy.Journal of Clinical Investigation, 1997
- Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathwaysNature, 1996
- FK506 in the treatment of inflammatory skin disease: promises and perspectivesImmunology Today, 1996
- INCREASED EXPRESSION OF IL-4 AND IL-10 AND DECREASED EXPRESSION OF IL-2 AND INTERFERON-γ IN LONG-SURVIVING MOUSE HEART ALLOGRAFTS AFTER BRIEF CD4-MONOCLONAL ANTIBODY THERAPY1,2Transplantation, 1995