HYPOPHOSPHATEMIC OSTEOMALACIA IN FIBROUS DYSPLASIA

  • 1 January 1976
    • journal article
    • research article
    • Vol. 45  (179) , 411-420
Abstract
Three patients with fibrous dysplasia of bone in whom there was evidence of hypophosphatemic osteomalacia or rickets. Two of the patients had polyostotic fibrous dysplasia and osteomalacia. The 3rd was a child with fibrous dysplasia of the facial and cranial bones and rickets. In all cases the manifestations of osteomalacia or rickets were controlled with large doses of vitamin D. In the child the rickets and hypophosphatemia ceased when most of the bone affected by fibrous dysplasia was surgically resected. Previously reported cases of the association between fibrous dysplasia and hypophosphatemic osteomalacia are reviewed. These cases may be analogous to the syndrome of tumor rickets where hypophosphatemia appears to be due to the presence of a mesenchymal tumor and regresses when the tumor is removed.

This publication has 1 reference indexed in Scilit: