Prevention of recurrent carcinoma of the colon and rectum

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Abstract
Summary and Conclusions Attention has been drawn to the limitations of surgical management of carcinoma of the colon and rectum and to methods that show promise of improving five-, ten-and 15-year salvage rates. More extensive use of new and existing methods of cancer detection, by both physician and patient, should be undertaken. Thus far, the results from the use of XCB appear to be encouraging and no untoward effects have been encountered in its use. The problem of recurrence by implantation still prevents a survival rate proportionate to the surgeon's efforts. In our series, sufficient time has not yet elapsed for a representative statistical report. Smears taken for cell study and chemical tissue reactions are being evaluated. More time and similar studies by other interested investigators will be required to justify more significant conclusions. It is not our purpose to champion the use of a specific drug or operative procedure, but rather to present a preliminary report on a method encompassing many factors directed primarily at lessening the incidence of local recurrence and implantation of malignant cells in the anastomosis.