Experience with a commercial kit for the radioisotopic assay of vitamin B12in serum: the Phadebas B12Test
- 1 January 1974
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 27 (1) , 59-65
- https://doi.org/10.1136/jcp.27.1.59
Abstract
The first commercial kit for the radioisotopic assay of vitamin B(12) in serum-the Phadebas B(12) Test produced higher values than the radioisotopic method of Raven, Robson, Walker, and Barkham (1969) and the Lactobacillus leichmannii microbiological assay. Its normal range was 300-1100 pg/ml and its reproducibility was similar to that of the other radioisotopic method. It should be possible to lower the results obtained by the Phadebas method by modifying its standard curve and to reduce the time taken for the assay by shortening its incubation period.Keywords
This publication has 18 references indexed in Scilit:
- Comparison of Two Radioassay Methods for Vitamin B12Clinical Chemistry, 1972
- Comparison of Three Methods for Measuring Vitamin B12 in Serum: Radioisotopic, Euglena gracilis and Lactobacillus leichmanniiBritish Journal of Haematology, 1972
- A Radiosorbent Technique for the Assay of Serum Vitamin B12Scandinavian Journal of Clinical and Laboratory Investigation, 1971
- Brief Report: Hemoglobin-Coated Charcoal Radioassay for Serum Vitamin B12. A Simple Modification To Improve Intrinsic Factor ReliabilityBlood, 1969
- Improved method for measuring vitamin B12in serum using intrinsic factor,57CoB12, and coated charcoalJournal of Clinical Pathology, 1969
- The effect of cyanide, serum and other factors on the assay of vitamin B12 by a radio-isotope method using 57CoB12, intrinsic factor and coated charcoal.1968
- Addisonian pernicious anaemia and intrinsic factor antibodies in thyroid disorders.1966
- Measurement of Serum Vitamin B12 Level Using Radioisotope Dilution and Coated CharcoalBlood, 1965
- OBSERVATIONS ON ESTIMATION OF SERUM VITAMIN B12 USING LACTOBACILLUS LEICHMANNII1962
- AN IMPROVED METHOD FOR THE RAPID ESTIMATION OF VITAMIN-B12 IN SERUM1955