Colony stimulating activity of serum from germfree normal and leukemic mice
Open Access
- 1 August 1967
- journal article
- research article
- Published by Wiley in Journal of Cellular Physiology
- Vol. 70 (1) , 131-132
- https://doi.org/10.1002/jcp.1040700118
Abstract
Serum from germfree Swiss/HaM mice exhibited a reduced capacity to stimulate granulocytic and mononuclear cell colony formation by DBA/1 bone marrow cells in vitro when compared with serum from conventional Swiss/HaM mice. Sera from germfree preleukemic and leukemic AKR mice exhibited strong colony stimulating activity, indicating that the increased colony stimulating activity previously observed in the serum of conventional leukemic mice is not the consequence of bacterial or fungal infections supervening in leukemic animals with deficient immune responses.This publication has 3 references indexed in Scilit:
- Stimulation by normal and leukemic mouse sera of colony formation in vitro by mouse bone marrow cellsJournal of Cellular Physiology, 1967
- Immune responses in preleukaemic and leukaemic AKR miceInternational Journal of Cancer, 1967
- Histologic and Transplantation Studies on Preleukemic Thymus of the AKR Mouse2JNCI Journal of the National Cancer Institute, 1966