The Formation of Histamine in the Rat
- 1 September 1961
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 13 (1) , 75-82
- https://doi.org/10.1111/j.2042-7158.1961.tb11791.x
Abstract
Factors affecting the determination of histidine decarboxylase activity in adult rat tissues have been studied. The optimal conditions vary from tissue to tissue, and the most potent sources of the enzyme are the pyloric part of the stomach, the liver and the duodenum, with less in the kidney. There is no relationship between the histidine decarboxylase activity of a rat tissue and the amount of histamine it contains.Keywords
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