Detergent Effects on a Reverse Transcriptase Activity and on Inhibition by Rifamycin Derivatives
- 3 November 1972
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 178 (4060) , 505-507
- https://doi.org/10.1126/science.178.4060.505
Abstract
A reverse transcriptase activity, extracted from virus-transformed cells, is activated by very low concentrations of nonionic detergents. These same detergents also significantly reduce the effectiveness of certain rifamycin derivatives as inhibitors of the polymerase activity when the detergents are present at micelle-forming concentrations.Keywords
This publication has 1 reference indexed in Scilit:
- Actions of the rifamycinsMicrobiology and Molecular Biology Reviews, 1971