Key Role of Ubc5 and Lysine-63 Polyubiquitination in Viral Activation of IRF3
- 23 October 2009
- journal article
- research article
- Published by Elsevier
- Vol. 36 (2) , 315-325
- https://doi.org/10.1016/j.molcel.2009.09.037
Abstract
No abstract availableKeywords
This publication has 45 references indexed in Scilit:
- The Zinc Finger of NEMO Is a Functional Ubiquitin-binding DomainJournal of Biological Chemistry, 2009
- The tumour suppressor CYLD is a negative regulator of RIG‐I‐mediated antiviral responseEMBO Reports, 2008
- Are the IKKs and IKK-related kinases TBK1 and IKK-ɛ similarly activated?Trends in Biochemical Sciences, 2008
- The C-Terminal Regulatory Domain Is the RNA 5′-Triphosphate Sensor of RIG-IMolecular Cell, 2008
- Lipopolysaccharide-mediated Interferon Regulatory Factor Activation Involves TBK1-IKKϵ-dependent Lys63-linked Polyubiquitination and Phosphorylation of TANK/I-TRAFJournal of Biological Chemistry, 2007
- TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activityNature, 2007
- Activation of IKK by TNFα Requires Site-Specific Ubiquitination of RIP1 and Polyubiquitin Binding by NEMOMolecular Cell, 2006
- IKKε and TBK1 are essential components of the IRF3 signaling pathwayNature Immunology, 2003
- Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin ChainPublished by Elsevier ,2000
- The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stressesCell, 1987