Two forms of the T-cell receptor γ protein found on peripheral blood cytotoxic T lymphocytes
- 1 February 1987
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 325 (6106) , 689-694
- https://doi.org/10.1038/325689a0
Abstract
The T-cell receptor (TCR) gamma polypeptide is expressed associated with CD3 (T3) on the surface of normal human peripheral blood lymphocytes. These cells function as non-MHC-restricted cytotoxic T lymphocytes (CTL)and thus may play an important role in host immune defence. The TCR gamma polypeptide occurs as a dimer in at least two molecular forms based on the absence or presence of disulphide linkage. These forms use TCR gamma polypeptides with strikingly different peptide backbone sizes.Keywords
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