CB 1954 (2,4-dinitro-5-aziridinyl benzamide) becomes a DNA interstrand crosslinking agent in Walker tumour cells
- 1 November 1986
- journal article
- research article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 140 (3) , 1073-1078
- https://doi.org/10.1016/0006-291x(86)90744-8
Abstract
No abstract availableThis publication has 10 references indexed in Scilit:
- The unique sensitivity of Walker rat tumour cells to difunctional agents is associated with a failure to recover from inhibiton of DNA synthesis and increased chromosome damageMutation Research/DNA Repair Reports, 1986
- Walker rat carcinoma cells are exceptionally sensitive to cis-diamminedichloroplatinum(II) (cisplatin) and other difunctional agents but not defective in the removal of platinum-DNA adductsMutation Research/DNA Repair Reports, 1986
- CB 1954 revisitedCancer Chemotherapy and Pharmacology, 1986
- Quantitative aspects of the formation and loss of DNA interstrand crosslinks in Chinese hamster cells following treatment with cis-diamminedichloroplatinum(II) (cisplatin) II. Comparison of results from alkaline elution, DNA renaturation and DNA sedimentation studiesBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1981
- Selective inhibition of ribonucleotide reductase by the monofunctional alkylating agent 5(1-aziridinyl)-2,4-dinitrobenzamide (CB 1954)Biochemical Pharmacology, 1980
- Protection against the effects of the antitumour agent CB 1954 by certain imidazoles and related compoundsBiochemical Pharmacology, 1975
- Studies on the reversal of the selective antitumour effect of the aziridinyl derivative cb 1954 by 4‐amino‐5‐imidazolecarboxamideInternational Journal of Cancer, 1972
- Quantitative aspects of the repair of alkylated DNA in cultured mammalian cellsChemico-Biological Interactions, 1971
- Studies on the mechanism of action of 5-aziridinyl-2,4-dinitrobenzamide (CB 1954), a selective inhibitor of the walker tumourInternational Journal of Cancer, 1971
- 2,4-Dinitro-5-ethyleneiminobenzamide (CB 1954): A potent and selective inhibitor of the growth of the Walker carcinoma 256Biochemical Pharmacology, 1969