Hypoglycemia in Type 1 and Type 2 Diabetes: Physiology, Pathophysiology,and Management
- 1 July 2006
- journal article
- Published by American Diabetes Association in Clinical Diabetes
- Vol. 24 (3) , 115-121
- https://doi.org/10.2337/diaclin.24.3.115
Abstract
IN BRIEF The threat and incidence of hypoglycemia is the major limiting factor in intensive glycemic control for both type 1 and type 2 diabetes. This article reviews the physiology of the normal counterregulatory responses to hypoglycemia and the deficient counterregulatory defenses that occur in patients with diabetes. Treatment paradigms for establishing good glycemic control while limiting hypoglycemia are also discussed.Keywords
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