INTERLEUKIN-1 FAMILY: FROM GENES TO HUMAN DISEASE
Open Access
- 1 July 2000
- journal article
- Published by Palacky University Olomouc in Biomedical Papers
- Vol. 144 (143) , 19-30
- https://doi.org/10.5507/bp.2000.002
Abstract
Interleukin-1 (IL-1) is one of the most potent proinflammatory cytokines involved both in physiologicalimmune responses and in the development of various immunopathological disorders. The members of IL-1 familyform a complex system with tight r...Keywords
This publication has 128 references indexed in Scilit:
- Mice Deficient in Interleukin-1 Converting Enzyme are Resistant to Neonatal Hypoxic-Ischemic Brain DamageJournal of Cerebral Blood Flow & Metabolism, 1999
- The IL-1 receptor and Rho directly associate to drive cell activation in inflammationJournal of Clinical Investigation, 1999
- The Interleukin-1 Receptor Antagonist Gene Shows No Allelic Association with Three Autoimmune DiseasesThyroid®, 1999
- Dynamic regulation of the proinflammatory cytokine, interleukin-1β: Molecular biology for non-molecular biologistsLife Sciences, 1999
- Interleukin-1 Receptor Cluster: Gene Organization ofIL1R2, IL1R1, IL1RL2(IL-1Rrp2),IL1RL1(T1/ST2), andIL18R1(IL-1Rrp) on Human Chromosome 2qGenomics, 1999
- Production of Mice Deficient in Genes for Interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 Receptor Antagonist Shows that IL-1β Is Crucial in Turpentine-induced Fever Development and Glucocorticoid SecretionThe Journal of Experimental Medicine, 1998
- Interleukin-18 Activates the IRAK-TRAF6 Pathway in Mouse EL-4 CellsBiochemical and Biophysical Research Communications, 1998
- Neutralization of endogenous IL-1 receptor antagonist exacerbates and prolongs inflammation in rabbit immune colitis.Journal of Clinical Investigation, 1994
- Colonic Mucosal Interleukin 1 Receptor Antagonist in Inflammatory Bowel DiseaseDigestion, 1994
- Cytokine production in patients with inflammatory bowel disease.Gut, 1992