Staphyloxanthin Plays a Role in the Fitness of Staphylococcus aureus and Its Ability To Cope with Oxidative Stress
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Open Access
- 1 August 2006
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 74 (8) , 4950-4953
- https://doi.org/10.1128/iai.00204-06
Abstract
Staphyloxanthin is a membrane-bound carotenoid of Staphylococcus aureus . Here we studied the interaction of staphyloxanthin with reactive oxygen substances (ROS) and showed by comparative analysis of the wild type (WT) and an isogenic crtM mutant that the WT is more resistant to hydrogen peroxide, superoxide radical, hydroxyl radical, hypochloride, and neutrophil killing.Keywords
This publication has 21 references indexed in Scilit:
- Structure and Biosynthesis of Staphyloxanthin from Staphylococcus aureusJournal of Biological Chemistry, 2005
- Recognition ofStaphylococcus aureusby the Innate Immune SystemClinical Microbiology Reviews, 2005
- Myeloperoxidase: friend and foeJournal of Leukocyte Biology, 2005
- Involvement of nitric oxide donor compounds in the bactericidal activity of human neutrophils in vitroJournal of Medical Microbiology, 2003
- Chlorination of Bacterial and Neutrophil Proteins during Phagocytosis and Killing of Staphylococcus aureusJournal of Biological Chemistry, 2002
- Identification of a novel antigen fromStaphylococcus epidermidisFEMS Immunology & Medical Microbiology, 2000
- The Haber–Weiss reaction and mechanisms of toxicityToxicology, 2000
- Reactions involving singlet oxygen and the superoxide anionNature, 1976
- Singlet Excited Oxygen as a Mediator of the Antibacterial Action of LeukocytesScience, 1974
- Staphylococcal Coagulase: Mode of Action and AntigenicityMicrobiology, 1952