Hyponatraemia Following Transurethral Resection of the Prostate

Abstract
In a prospective study of 100 patients undergoing transurethral resection (TUR), changes in serum Na were estimated during the peroperative and postoperative periods. The weight of prostate resected and the volume of irrigant fluid used influenced the changes in serum Na. In 93 patients these changes were not statistically significant. In only 7 patients were significant falls in serum Na recorded, in 1 case to a level of 103 mmol/l. All 7 exhibited the clinical features of the transurethral syndrome and there was 1 postoperative death which was attributed to it. The TUR syndrome undoubtedly exists and its incidence in this series was 7%. Its pathogenesis and clinical management are discussed.