Terminoside A, a new triterpene glycoside from the bark ofTerminalia arjunainhibits nitric oxide production in murine macrophages
- 1 June 2003
- journal article
- research article
- Published by Taylor & Francis in Journal of Asian Natural Products Research
- Vol. 5 (2) , 137-142
- https://doi.org/10.1080/1028602031000066834
Abstract
Terminoside A (1), a new oleanane-type triterpene was isolated from the acetone fraction of the ethanolic extract of stem bark of Terminalia arjuna. The structure was established as olean-1α,3β,22β-triol-12-en-28-oic acid-3β-D-glucopyranoside. On the basis of spectral data and chemical reactions, terminoside A, potently inhibited nitric oxide (NO) production and decreased inducible nitric oxide synthase (iNOS) levels in lipopolysaccharide-stimulated macrophages.Keywords
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