GENOTYPING STUDY OF ALCOHOL DEHYDROGENASE CLASS I POLYMORPHISM IN FRENCH PATIENTS WITH ALCOHOLIC CIRRHOSIS
- 1 November 1990
- journal article
- research article
- Published by Oxford University Press (OUP) in Alcohol and Alcoholism
- Vol. 25 (6) , 623-626
- https://doi.org/10.1093/oxfordjournals.alcalc.a045058
Abstract
Comparison of alcohol dehydrogenase polymorphism at the loci ADH 2 and ADH 3 is made in France between 46 alcoholic cirrhotic patients and 39 controls, by genotyping technique using polymerase chain reaction on blood microsample collected on blotting paper. The genotype distributions are similar, with low frequency of the ADH 22 allele. Polymorphism at the ADH 3 locus is not a genetic factor for alcoholic cirrhosis in France.Keywords
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