MULTI-CENTER DOUBLE-BLIND EFFICACY AND SAFETY STUDY COMPARING ALPRAZOLAM, DIAZEPAM AND PLACEBO IN CLINICALLY ANXIOUS PATIENTS
- 1 January 1981
- journal article
- research article
- Vol. 42 (9) , 347-351
Abstract
Both alprazolam and diazepam were superior to placebo for the treatment of the clinical anxiety syndrome throughout a 4-wk double-blind multiclinic trial of 976 outpatients. At the 4th-wk evaluation of the 845 patients completing the study, the 326 patients receiving alprazolam showed significantly more improvement than the 344 patients receiving diazepam on all 4 anxiety rating scales utilized (Hamilton Anxiety Rating Scale, Physician''s Global Assessment, Patient''s Global Assessment and Target Symptoms).This publication has 2 references indexed in Scilit:
- Anxiolytic Efficacy of Alprazolam Compared to Diazepam and PlaceboJournal of International Medical Research, 1980
- Pharmacology of some metabolites of triazolam, alprazolam, and diazepam prepared by a simple, one-step oxidation of benzodiazepinesJournal of Medicinal Chemistry, 1978