Synthesis of aminocyclitol moieties of trehalase inhibitors, trehalostatin and trehazolin. Correct structure of the inhibitor
- 1 January 1992
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 12,p. 886-888
- https://doi.org/10.1039/c39920000886
Abstract
The respective aminocyclitol moieties 3a and 4a of trehalostatin 1 and trehazolin 2, potent trehalase inhibitors, are synthesized as the N,O-pentaacetyl derivatives 3b and 4b in racemic form, in order both to establish the structure of the inhibitor and to provide a synthon useful for its total synthesis.Keywords
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