Intermediates in the Barnol Biosynthesis in Penicillium baarnense.

Abstract
By using appropriate 14C-labeled phenolic substances as precursors in feeding experiments the following steps in barnol biosynthesis were established: acetate + malonate .fwdarw. 2,4-dihydroxy-6-ethyl-5-methylbenzaldehyde .fwdarw. 1,3-dihydroxy-4,6-dimethyl-2-ethylbenzene .fwdarw. barnol P. baarnense can reduce orcylaldehyde and 2,4-dihydroxy-5,6-dimethylbenzaldehyde to dimethylresorcinol and trimethylresorcinol, respectively.

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